Archive for July 13, 2015

mangosteenA tropical fruit native to Southeast Asia has been shown in a new study to protect against breast cancer. Researchers from the University of Chinese Academy of Sciences’ (UCAS) College of Life Sciences found that the pericarp of the mangosteen fruit, which is commonly grown in Thailand and Malaysia, contains a unique compound that triggers apoptosis, or cell death, in breast cancer cells.

A followup to a previous study on mangosteen’s effects in vitro, this latest research looked at the effects of a unique mangosteen xanthone on actual human breast cancer cells. The team from UCAS studied how alpha-mangostin affects fatty acid synthase, or FAS, a multi-enzyme protein that catalyzes the formation of long-chain fatty acids from various compounds. Over-expression of FAS is also commonly observed in conjunction with breast cancer occurrence.

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